voriconazole will enhance the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.apalutamide will lower the extent or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with medi